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MedPage Today’s October 25, 2026, roundup collected comments from clinicians and researchers on dengue outbreaks, multiple sclerosis, pregnancy and medication exposure, menopause treatments, advance care planning and early psilocybin research. The remarks summarize separate reports and studies; several findings are preliminary or leave important questions unanswered.
MedPage Today published a weekly roundup of medical quotes on October 25, 2026, featuring comments on dengue outbreaks in Florida, an incorrect multiple sclerosis diagnosis, menopause treatments and early research into psilocybin. The collection brings together reactions to separate reports and studies; it is not a single study or new clinical guideline, and several topics remain uncertain or preliminary.
The roundup’s opening quote came from Adam Waickman, a researcher at SUNY Upstate Medical University, who said, “The cat is out of the bag” while discussing large dengue outbreaks in Florida and warning of potential further spread across the United States. The source does not provide outbreak figures, a forecast, or additional details about the risk in other states.
Other comments addressed questions about treatment and diagnosis. Christina Chambers of the University of California San Diego called it “an open question” whether early-life exposure to dupilumab, sold as Dupixent, could reduce children’s long-term risk of atopic conditions. The roundup says data indicated exposure during pregnancy appeared safe, but it does not give study details or establish a preventive effect. Cleveland Clinic neurologist Marisa McGinley said an incorrect multiple sclerosis diagnosis “does happen,” in reference to actress Christina Applegate’s diagnosis.
The collection also cited a report about an exceptionally rare infant case in which a second colon was found after constipation had been treated as straightforward. Lynn Sinitsky of West Hertfordshire Teaching Hospitals NHS Trust said clinicians had attributed the symptoms to constipation without first considering another cause. On menopause care, Harvard’s JoAnn Manson called findings from a meta-analysis “good news for women,” saying non-hormonal drugs could ease sleep disturbances. The roundup offered no drug names or effect sizes.
What the Findings Could Mean
The collection matters because it puts several issues affecting patients and clinicians into view, while also showing how different the evidence behind each item can be. A warning about dengue spread, a meta-analysis of menopause medicines, an unusual case report and a small trial do not carry the same weight or answer the same questions. Readers should not treat the quotations as equivalent proof or as medical advice.
Some comments point to practical questions in care: whether symptoms merit a broader diagnostic work-up, how clinicians can support patients in planning for future care, and what information patients need when considering treatments. Others describe research that could guide future investigation rather than change care now. The distinction between an early signal and an established clinical benefit is particularly relevant to the dupilumab and psilocybin findings.
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The Reports Behind the Quotes
MedPage Today presented the material as “quotable quotes” heard by its reporters, not as a unified research paper. The cited comments relate to different stories and evidence types. The source mentions a meta-analysis on non-hormonal menopause drugs, a small trial involving psilocybin and Parkinson’s disease, and research on a video decision-support tool for people nearing kidney failure.
In the latter work, Angelo Volandes of Dartmouth Health said the tool increased documentation of advance care planning. He argued that medical records should preserve what matters to patients as well as what is medically wrong. The roundup does not state the size of the study, the degree of change in documentation, or whether the tool affected patient outcomes.
Ellen Bradley of UCSF said a small trial linking psilocybin with reduced markers of systemic inflammation and mitochondrial stress in patients with Parkinson’s disease raised biological questions for researchers. The source describes changes in markers, not evidence that psilocybin treats Parkinson’s disease or improves symptoms.
““This is good news for women.””
— JoAnn Manson, MD, MPH, DrPH, Harvard Medical School
Evidence Gaps Across the Stories
The roundup does not supply the underlying studies, full methods, sample sizes for most findings, or numerical results. It is therefore not possible from this source alone to judge the strength or limits of each result. The dengue warning is not accompanied by a defined geographic forecast or timeline, and the extent of any spread beyond Florida remains unspecified.
Questions also remain about whether pregnancy exposure to dupilumab is safe across different circumstances and whether it affects children’s long-term risk of atopic conditions. The roundup says pregnancy exposure “appeared safe,” but does not describe the evidence or follow-up period. The menopause finding lacks drug-specific details, while the psilocybin result concerns biological markers in a small trial and does not establish a clinical benefit.
The source does not give details of the infant’s diagnosis, the circumstances surrounding Applegate’s incorrect MS diagnosis, or the scale and patient impact of the advance care planning project. Those reports should be read within their original clinical and research settings.
Further Reporting and Research
The roundup does not announce a specific next milestone or provide publication dates for follow-up studies. Further reporting on the individual stories would be needed to establish the dengue situation, explain the evidence behind pregnancy exposure to dupilumab, and provide the full results of the menopause meta-analysis and kidney-care project.
For the early psilocybin findings, larger and more detailed studies would be needed to determine whether changes in inflammation or mitochondrial-stress markers have clinical relevance. The long-term effects of early-life dupilumab exposure also remain a research question. Until more evidence is available, the roundup’s comments offer a snapshot of current discussion rather than a basis for changing treatment or public-health decisions on their own.
Key Questions
What did MedPage Today publish?
It published a weekly collection of quotations from reporters’ medical coverage on October 25, 2026. The quotes concern several separate stories, not one new study.
Did the roundup confirm dengue is spreading across the United States?
No. Adam Waickman warned of possible further spread while discussing large outbreaks in Florida, but the roundup gives no national case figures or specific forecast.
Does the source say dupilumab prevents atopic conditions in children?
No. Christina Chambers described that possibility as an open question. The roundup says pregnancy exposure appeared safe in the cited data but does not establish a preventive effect.
Do the psilocybin findings show it treats Parkinson’s disease?
No. The roundup describes a small trial associated with reduced markers of systemic inflammation and mitochondrial stress. It does not report that psilocybin improved symptoms or treated the disease.
Can the roundup’s comments guide individual treatment decisions?
The quotes summarize different reports and vary in evidence strength. They are not a substitute for the original studies or clinical advice from a qualified health professional.
Source: rss
